ToxServices’ Full Material Disclosure (ToxFMD) Screened Chemistry® is ToxServices’ flagship program for evaluating chemical formulations and conducting product stewardship audits.

ToxServices is accredited by the ZDHC to verify conformance with ZDHC MRSL Levels 1, 2, and 3 requirements.  ToxFMD® is used by brands around the world to eliminate chemicals of concern.

ToxFMD® Level 1, 2, and 3 are equivalent to ZDHC MRSL Level 1, 2, and 3.


ToxFMD | Screened Chemistry | textiles | ScreenedChemistry | ToxServices

ToxFMD | Screened Chemistry | textiles


ToxServices established Screened Chemistry in 2014 in conjunction with Levi Strauss & Co. with the goal of advancing public health and environmental protection around the world. Screened Chemistry is the concept of identifying the use of safer alternatives while eliminating hazardous chemicals in the textile industry.  In a Screened Chemistry approach, human health and environmental impacts are fully evaluated so dangerous chemical substitutions are avoided. 

Levi Strauss & Co., Nike Inc., H&M and C&A have agreed to share and align their efforts surrounding safer textile chemistries as part of their work with the ZDHC Foundation. ToxServices’ Full Materials Disclosure® Program (ToxFMD®) is an integral part of the Levi Strauss & Co. Screened Chemistry Program and supports hazard reduction and informed substitution.

ToxFMD Screened Chemistry® Program is our flagship certificate program to demonstrate conformance with Screened Chemistry requirements. ToxFMD Screened Chemistry® provides a streamlined, affordable assessment that screens textile treatment formulations and allows ZDHC brands to easily identify safer alternatives and fulfill their commitment to using safer textile auxiliaries.

There are three levels of ToxFMD® assessment:

  • ToxFMD® Level 1 evaluation: This assessment is designed to assess hazards and MRSL level conformance of a formulation

  • ToxFMD® Level 2 evaluation: This assessment is designed to verify that systems or processes are place to minimize the release of hazardous chemicals to environment (air, water, soil), and that health and safety practices are in place to protect workers.  This is a desk audit and does not require an on-site visit.

  • ToxFMD® Level 3 evaluation: The requirements of a ToxFMD® Level 3 evaluation are identical to a ToxFMD® Level 2 evaluation, with the exception that an on-site visit to the chemical supplier is performed as part of a ToxFMD® Level 3 evaluation to evaluate chemicals stewardship and environmental management systems first-hand.  



ZDHC MRSL Level 1 Conformance



Full disclosure (to ToxServices) of all intentionally added ingredients present at any concentration, and residuals or impurities present at or above 0.01% (100 ppm) in the formulation. 


Note: for substances with ZDHC MRSL v. 2.0 limits that are < 100 ppm, supplier disclosure must be sufficient to determine whether such chemicals are present at levels greater than their ZDHC MRSL v. 2.0 limits. If not, testing may be required.

ToxFMD Screened Chemistry® Level 1 Conformance

= ZDHC MRSL v. 2.0 Level 1 Conformance


Formulation assessed against the ZDHC Manufacturing Restricted Substances List (MRSL) (v. 2.0)

Formulation assessed against the U.S. EPA Safer Chemical Ingredients List (SCIL)

Formulation assessed against the GreenScreen® (GS) List Translator (LT) to identify LT-1 listed chemicals

Perform an LT-1 Summary assessment of any chemical identified as an LT-1 by the GS List Translator

Perform a GreenScreen® assessment for any intentionally added non-polymeric chemical not on the SCIL, and perform a GreenScreen® assessment for monomers > 0.1% in polymeric ingredients

Perform a ToxFMD® polymer assessment of any intentionally added polymeric ingredient, and perform Safer Choice functional class criteria screen for residuals > 0.01% in the formula

Calculate the Screened Chemistry score:

  • Preferred: > 35 - < 50

  • Needs Improvement: > 20 - < 35

  • Phase Out: < 2



The ToxFMD® Review has determined that chemicals present in the product formulation are:

  • Not listed on the ZDHC MRSL v. 2.0 of Hazardous Chemicals at or above the specified formulation limit

  • Considered "Acceptable" under the ToxFMD® Program Criteria

    • Not classified for carcinogenicity, mutagenicity, or reprotoxicity (CMR) or non-CMR human health hazards

    • Not classified for environmental toxicity and fate hazards


  • Considered "ToxFMD® Not Acceptable – Low Priority"

    • Classified for human health or environmental toxicity and fate endpoints, but is not classified as a high hazard for CMR endpoints and is not persistent, bioaccumulative, or toxic (PBT)​

  • Once awarded your ToxFMD Screened Chemistry® Certificate, your formulation will be added to the partnering ZDHC brands’ shared Preferred Formulation List (PFL), generating increased sales for your formulations 

  • Additionally, your formulation will be eligible to be listed in ZDHC Gateway – Chemical Module, an advanced search engine for formulations that are conforming to ZDHC's MRSL





The ToxFMD® Review has determined that at least one chemical present in the product formulation is:

  • Listed on the ZDHC MRSL v. 2.0 of Hazardous Chemicals at or above the specified formulation limit

  • Considered "Not Acceptable – High Priority" under the ToxFMD® Program Criteria

    • Classified as a high hazard for CMR endpoints and/or is a PBT



Suppliers from 24 Countries Have ToxFMD® Screened Chemistry Certificates
  • Argentina

  • Austria

  • Bangladesh

  • Belgium

  • China

  • Colombia

  • Dominican Republic

  • Germany

  • Hong Kong

  • India

  • Italy

  • Japan

  • Malaysia

  • Mexico

  • Singapore

  • Spain

  • Sri Lanka

  • Switzerland

  • Taiwan

  • The Netherlands

  • Thailand

  • Turkey

  • United Kingdom

  • United States

Formulations from 44 Different Functional Categories Have Been Assessed 
  • Acid Dye

  • Anti Crease Agent

  • Anti-Back Staining Agent

  • Anti-Pilling Agent

  • Biocide

  • Bioscoring Agent

  • Bleach

  • Bleach Booster

  • Bleaching Agent

  • Buffer

  • Catalyst

  • Cationizing Agent

  • Desizing Agent

  • Desizing-Stonewashing Agent

  • Detergent

  • Disperse Agent

  • Durable Water Repellent

  • Fixing Agent

  • Flame Retardant

  • Gelling Agent

  • Glossing Agent

  • Glue

  • Leveling Agent

  • Mercerizing Agent

  • N/A

  • Neutralizing Agent

  • Odor Control

  • Optical Brightening Agent

  • Paraffin Wax Emulsion

  • Pigment

  • Protecting Agent

  • Reducing Agent

  • Reserving Agent

  • Salt Oxidizer

  • Sequestering Agent

  • Sizing Agent

  • Softener

  • Stabilizer

  • Stiffener

  • Stonewashing Agent

  • Surfactant

  • Thickener

  • Wax Softener

  • Wetting Agent


ToxServices was founded in 2003 by Managing Director & Chief Toxicologist Dr. Margaret H. Whittaker. The scientists at ToxServices offer more than a decade of expertise in toxicology, risk assessment, comparative hazard assessment, and the application of science to promote human health and environmental sustainability.


Our head offices are in Washington, D.C. and Ann Arbor, Michigan. We have professionals located across North America and the United Kingdom who work with clients across the across the globe, including North America, Central America, South America, Europe, and Asia.


ToxServices' aim is to resolve complex human health and environmental issues through the application of sound science, risk assessment and the principles of environmental sustainability and to continue to evolve and expand services as environmental and human health needs require.



Obtain a quote for ToxFMD
Screened Chemistry® services.

For quotes, inquiries or a discussion about our services, please call +1 202 429-8787 (USA) or complete the form below.

Limited Time Special Offer!

Receive a free 6-month trial of ToxFMD Screened Chemistry® Library after you have completed your first ToxFMD review.

Head Office

1367 Connecticut Avenue, N.W.,

Suite 300

Washington, D.C. 20036

United States of America

+1 (202) 429 8787
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