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ToxServices’ Full Material Disclosure (ToxFMD) Screened Chemistry® is ToxServices’ flagship program for evaluating chemical formulations and conducting product stewardship audits.

ToxServices is accredited by the ZDHC to verify conformance with ZDHC MRSL Levels 1, 2, and 3 requirements.  ToxFMD® is used by brands around the world to eliminate chemicals of concern.

ToxFMD® Level 1, 2, and 3 are equivalent to ZDHC MRSL Level 1, 2, and 3.



ToxFMD | Screened Chemistry | textiles | ScreenedChemistry | ToxServices

ToxFMD | Screened Chemistry | textiles


ToxServices established Screened Chemistry in 2014 in conjunction with Levi Strauss & Co. with the goal of advancing public health and environmental protection around the world. Screened Chemistry is the concept of identifying the use of safer alternatives while eliminating hazardous chemicals in the textile industry.  In a Screened Chemistry approach, human health and environmental impacts are fully evaluated so dangerous chemical substitutions are avoided. 

Levi Strauss & Co., Nike Inc., H&M and C&A have agreed to share and align their efforts surrounding safer textile chemistries as part of their work with the ZDHC Foundation. ToxServices’ Full Materials Disclosure® Program (ToxFMD®) is an integral part of the Levi Strauss & Co. Screened Chemistry Program and supports hazard reduction and informed substitution.

ToxFMD Screened Chemistry® Program is our flagship certificate program to demonstrate conformance with Screened Chemistry requirements. ToxFMD Screened Chemistry® provides a streamlined, affordable assessment that screens textile treatment formulations and allows ZDHC brands to easily identify safer alternatives and fulfill their commitment to using safer textile auxiliaries.

There are three levels of ToxFMD® assessment:

  • ToxFMD® Level 1 evaluation: This assessment is designed to assess hazards and MRSL level conformance of a formulation

  • ToxFMD® Level 2 evaluation: This assessment is designed to verify that systems or processes are place to minimize the release of hazardous chemicals to environment (air, water, soil), and that health and safety practices are in place to protect workers.  This is a desk audit and does not require an on-site visit.

  • ToxFMD® Level 3 evaluation: The requirements of a ToxFMD® Level 3 evaluation are identical to a ToxFMD® Level 2 evaluation, with the exception that an on-site visit to the chemical supplier is performed as part of a ToxFMD® Level 3 evaluation to evaluate chemicals stewardship and environmental management systems first-hand.  



ZDHC MRSL Level 1 Conformance


Fabric in Rolls

Full disclosure (to ToxServices) of all intentionally added ingredients present at any concentration, and residuals or impurities present at or above 0.01% (>100 ppm) in the formulation. 

ToxFMD v.3 Flowchart.png

ToxFMD Screened Chemistry® Process

Illustration of ToxFMD Level 1 Certifica

ToxFMD Screened Chemistry® Level 1 Conformance

= ZDHC MRSL v. 2.0 Level 1 Conformance


Test formulation by chemical analysis to demonstrate compliance with ZDHC Manufacturing Restricted Substances List (MRSL) v. 2.0

Screen ingredients and residuals through Priority List (ZDHC MRSL v. 2.0, AFIRM RSL, ChemSec SIN List, ZDHC MRSL v. 2.0 Candidate List) and Positive List (U.S. EPA SCIL)

Screen ingredients and residuals for dermal sensitization

Perform a GreenScreen® assessment for any intentionally added non-polymeric, non-colorant not on the SCIL, and perform a GreenScreen® assessment for monomers > 0.1% in polymers

Perform a ToxFMD® polymer assessment of any intentionally added polymeric ingredient and perform Safer Choice functional class criteria screen for residuals > 0.01% in formula or colorants at any level in formula

Calculate Screened Chemistry score for each ingredient and impurity

Calculate formulation’s Screened Chemistry score (0 to 50 points) based on ingredients’ Priority List Score (Max 0) + Comprehensive Hazard Assessment Score (Max 45) + Dermal Sensitization Score (Max 5):

  • Preferred: > 35 - < 50 points

  • Needs Improvement: > 20 - < 35 points

  • Phase Out: < 20 points


The ToxFMD® Review has determined that:

  • Formulation complies with ZDHC MRSL v. 2.0


  • ToxFMD Screened Chemistry® Score is > 20

  • Once awarded your ToxFMD Screened Chemistry® Certificate, your formulation will be added to the partnering ZDHC brands’ shared Preferred Chemical List (PCL) and to CleanChain, providing global visibility of your formulation

  • Additionally, your formulation will be eligible to be listed in ZDHC Gateway – Chemical Module, an advanced search engine for formulations that are conforming to ZDHC's MRSL



The ToxFMD® Review has determined:

  • At least one chemical present in the product formulation is listed on the ZDHC MRSL v. 2.0 at or above the specified MRSL limit

  • ToxFMD Screened Chemistry® Score is < 20



Suppliers from 24 Countries Have ToxFMD® Screened Chemistry Certificates
  • Argentina

  • Austria

  • Bangladesh

  • Belgium

  • China

  • Colombia

  • Dominican Republic

  • Germany

  • Hong Kong

  • India

  • Italy

  • Japan

  • Malaysia

  • Mexico

  • Singapore

  • Spain

  • Sri Lanka

  • Switzerland

  • Taiwan

  • The Netherlands

  • Thailand

  • Turkey

  • United Kingdom

  • United States

Formulations are Assessed from 54 Different Functional Categories 
  • Anti-Backstaining Agent

  • Anti-Crease Agent

  • Anti-Pilling Agent

  • Biocide

  • Bioscoring Agent

  • Bleach

  • Bleach Booster

  • Bleaching Agent

  • Buffer

  • Catalyst

  • Cationizing Agent

  • Desizing Agent

  • Desizing-Stonewashing Agent

  • Detergent

  • Disperse Agent

  • Durable Water Repellent (DWR)

  • Dye - Acid

  • Dye - Azoic

  • Dye - Basic

  • Dye - Direct

  • Dye - Dispersant

  • Dye - Mordant

  • Dye - Reactive

  • Dye - Sulfur

  • Dye - Vat

  • Fixing Agent

  • Flame Retardant

  • Gelling Agent

  • Glossing Agent

  • Glue

  • Leveling Agent

  • Mercerizing Agent

  • N/A

  • Neutralizing Agent

  • Odor Control

  • Optical Brightening Agent

  • Paraffin Wax Emulsion

  • Pigment - Inorganic

  • Pigment - Organic

  • Printing Agent

  • Protecting Agent

  • Reducing Agent

  • Reserving Agent

  • Salt Oxidizer

  • Sequestering Agent

  • Sizing Agent

  • Softener

  • Stabilizer

  • Stiffener

  • Stonewashing Agent

  • Surfactant

  • Thickener

  • Wax Softener

  • Wetting Agent


ToxServices was founded in 2003 by Managing Director & Chief Toxicologist Dr. Margaret H. Whittaker. The scientists at ToxServices offer more than a decade of expertise in toxicology, risk assessment, comparative hazard assessment, and the application of science to promote human health and environmental sustainability.


Our head offices are in Washington, D.C. and Ann Arbor, Michigan. We have professionals located across North America and the United Kingdom who work with clients across the across the globe, including North America, Central America, South America, Europe, and Asia.


ToxServices' aim is to resolve complex human health and environmental issues through the application of sound science, risk assessment and the principles of environmental sustainability and to continue to evolve and expand services as environmental and human health needs require.



Obtain a quote for ToxFMD
Screened Chemistry® services.

For quotes, inquiries or a discussion about our services, please call +1 202 429-8787 (USA) or complete the form below.

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Limited Time Special Offer!

Receive a free 6-month trial of ToxFMD Screened Chemistry® Library after you have completed your first ToxFMD review.

Head Office

1367 Connecticut Avenue, N.W.,

Suite 300

Washington, D.C. 20036

United States of America

+1 (202) 429 8787
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